IDENTIFICATION OF POTENTIAL SMALL MOLECULE ALLOSTERIC MODULATOR SITES ON IL-1R1 ECTODOMAIN USING ACCELERATED CONFORMATIONAL SAMPLING METHOD.

Identification of potential small molecule allosteric modulator sites on IL-1R1 ectodomain using accelerated conformational sampling method.

The interleukin-1 receptor (IL-1R) is the founding member of the interleukin 1 receptor family which activates innate immune response by its binding to cytokines.Reports showed dysregulation of cytokine production leads to aberrant immune cells activation which contributes to auto-inflammatory disorders and diseases.Current therapeutic strategies f

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UHF RFID Channel Emulation Testbed for Wireless IoT Systems

We propose an ultra high frequency (UHF) radio frequency identification (RFID, 902–928 MHz in Overlay Grip Switch the US) channel emulation testbed that is capable of simultaneously emulating unique wireless channels.The proposed system can potentially be an invaluable tool in the design and validation of RFID-based Internet of Things (IoT)

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